胎膜促肾上腺素皮质激素释放激素受体表达与社会因素剖宫产的相关性
眭鸿颖 朱付凡 陶光实 施小六 黄健 2005-12-13 13:08:54 中华中西医杂志 2004年6月第5卷第11期
【摘要】 目的 探讨胎膜促肾上腺素皮质激素释放激素受体(CRHR1)mRNA表达与社会因素剖宫产的相关性。方法 采用半定量逆转录聚合酶链反应(RT-PCR)检测10例顺产、20例社会因素剖宫产产妇的胎膜上CRHR1mRNA的表达,分析其表达差异与社会因素剖宫产的相关性。结果 CRHR1mRNA在顺产产妇的胎膜中的表达显著高于社会因素剖宫产产妇的胎膜(P<0.05)。结论 社会因素剖宫产产妇胎膜中CRHR1mRNA表达较顺产者表达下调,提示CRHR1基因表达差异与社会因素剖宫产可能相关。
关键词 分娩方式 促肾上腺皮质激素释放激素受体 基因 聚合酶链反应 胎膜
Expression of corticotropin-releasing hormone receptor subtype1mRNA in
fetal membrane and the correlation to term elective cesarean section
on psychological factors Sui Hongying,
Zhu Fufan,Tao Guangshi,et al.
Department of Obstetrics and Gynecology,The Second Affiliated Hospital of Xiang Ya Medical College of Central South University,Changsha410011.
【Abstract】 Objective To investigate the expression of corticotropin-releasing hormone receptor subtype1(CRHR1)mRNA in fetal membrane whether related to the term elective cesarean section on psychological factors.Methods We detected CRHR1mRNA in fetal membrane of10vaginal delivery,20elective cesarean section on psyˉchological factors in late pregnant women by semi-quantity reverse transcrip
Key words delivery mode corticotropin-releasing hormone receptor genes polymerase chain reaction fetal membrane